MolNFT v1 · #183227 · protein
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation)
7NIV: “Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded…”. Electron microscopy, 2 ligands (CLR, DLP). MolNFT v1 #183227 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7NIV
- Type
- protein
- Length
- 2,020 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P21439
- Ligands
- CLR, DLP
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D | — | protein | 208 | — | — |
| E | — | protein | 229 | — | — |
| A | — | protein | 1138 | — | P21439 |
| B | — | protein | 211 | — | — |
| C | — | protein | 234 | — | — |
Ligands and binding sites
- CLR · Cholesterol · ligand · 7 copies · chains A
- DLP · 1,2-dilinoleoyl-sn-glycero-3-phosphocholine · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7NIV · Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab… · the same entry in another collection · chain D against D, TM-score 1.00
- P21439 · AlphaFold monomer V2.0 prediction for phosphatidylcholine translocator ABCB4 (P21439) · a predicted model of the same protein · chain A against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21439
- Elsewhere: RCSB PDB 7NIV · PDBe 7NIV · UniProt P21439
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