MolNFT v1 · #182196 · protein

Vascular katp channel: KIR6.1 SUR2B quatrefoil-like conformation 2

7MJQ: “Vascular katp channel: KIR6.1 SUR2B quatrefoil-like conformation 2”. Electron microscopy, 3 ligands (ATP, NAG, K). MolNFT v1 #182196 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7MJQ
Type: protein
Length: 2,982 residues
Chains: 6
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q63664, Q63563
Ligands: ATP, NAG, K

Structure

electron microscopy · 5 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	346	—	Q63664
B, D	—	protein	337	—	Q63664
C	—	protein	338	—	Q63664
E	—	protein	1426	—	Q63563
G	—	protein	198	—	Q63563

Ligands and binding sites

ATP · Adenosine-5'-triphosphate · ligand · 5 copies · chains A, D, B, C, E
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains E, G
K · Potassium ion · metal

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7MJQ · Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 2 · the same entry in another collection · chain G against G, TM-score 1.00
Q63563 · AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family C member 9 (Q63563) · a predicted model of the same protein · chain G against A, TM-score 0.88
Q63664 · AlphaFold monomer V2.0 prediction for ATP-sensitive inward rectifier potassium channel 8… · a predicted model of the same protein · chain C against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q63664
Every structure of UniProt Q63563
Elsewhere: RCSB PDB 7MJQ · PDBe 7MJQ · UniProt Q63664 · UniProt Q63563

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