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Vascular katp channel: KIR6.1 SUR2B quatrefoil-like conformation 2

Analyse Vascular katp channel: KIR6.1 SUR2B quatrefoil-like conformation 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7MJQ
Type
protein
Length
2,982 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q63664, Q63563
Ligands
ATP, NAG, K

Structure

electron microscopy · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein346—Q63664
B, D—protein337—Q63664
C—protein338—Q63664
E—protein1426—Q63563
G—protein198—Q63563

Ligands and binding sites

  • ATP · Adenosine-5'-triphosphate · ligand · 5 copies · chains A, D, B, C, E
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains E, G
  • K · Potassium ion · metal

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7MJQ · Vascular KATP channel: Kir6.1 SUR2B quatrefoil-like conformation 2 · the same entry in another collection · chain G against G, TM-score 1.00
  • Q63563 · AlphaFold monomer V2.0 prediction for ATP-binding cassette sub-family C member 9 (Q63563) · a predicted model of the same protein · chain G against A, TM-score 0.88
  • Q63664 · AlphaFold monomer V2.0 prediction for ATP-sensitive inward rectifier potassium channel 8… · a predicted model of the same protein · chain C against A, TM-score 0.83

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