MolNFT v1 · #182017 · protein

The internal aldimine form of the wild-type salmonella typhimurium tryptophan synthase in complex with N-(4'-trifluoromethoxybenzoyl)-2- amino-1-ethylphosphate (F6F) inhibitor at the beta-site, sodium ion at the metal coordination site and dual beta-Q114 rotamer conformation at 1.60 ångström resolution

7ME8: “The internal aldimine form of the wild-type salmonella typhimurium tryptophan synthase in complex with…”. X-ray diffraction, 3 ligands (PLP, F6F, NA). MolNFT v1 #182017 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7ME8
Type: protein
Length: 645 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P00929, P0A2K1
Ligands: PLP, F6F, NA

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	252	—	P00929
B	—	protein	393	—	P0A2K1

Ligands and binding sites

PLP · Pyridoxal-5'-phosphate · ligand · chains B
F6F · 2-{[4-(trifluoromethoxy)benzoyl]amino}ethyl dihydrogen phosphate · ligand · chains B
NA · Sodium ion · metal · chains B
EDO · 1,2-ethanediol · additive · chains A
PEG · Di(hydroxyethyl)ether · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7ME8 · The internal aldimine form of the wild-type Salmonella Typhimurium Tryptophan Synthase in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00929
Every structure of UniProt P0A2K1
Elsewhere: RCSB PDB 7ME8 · PDBe 7ME8 · UniProt P00929 · UniProt P0A2K1

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