MolNFT v1 · #181535 · protein
Structure of plasmodium falciparum 20S proteasome with bound bortezomib
7LXT: “Structure of plasmodium falciparum 20S proteasome with bound bortezomib”. Electron microscopy, 1 ligand (BO2). MolNFT v1 #181535 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LXT
- Type
- protein
- Length
- 6,318 residues
- Chains
- 28
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8IAR3, C6KST3, Q8IDG3, Q8IDG2, Q8IBI3, Q8IK90, O77396, Q8I0U7, Q8I6T3, Q8I261, Q8IKC9, Q8IJT1, A0A5K1K7U1, Q7K6A9
- Ligands
- BO2
Structure
electron microscopy · 14 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, O | — | protein | 252 | — | Q8IAR3 |
| B, P | — | protein | 227 | — | C6KST3 |
| C, Q | — | protein | 242 | — | Q8IDG3 |
| D, R | — | protein | 233 | — | Q8IDG2 |
| E, S | — | protein | 233 | — | Q8IBI3 |
| F, T | — | protein | 235 | — | Q8IK90 |
| G, U | — | protein | 240 | — | O77396 |
| H, V | — | protein | 220 | — | Q8I0U7 |
| I, W | — | protein | 218 | — | Q8I6T3 |
| J, X | — | protein | 215 | — | Q8I261 |
| K, Y | — | protein | 195 | — | Q8IKC9 |
| L, Z | — | protein | 209 | — | Q8IJT1 |
| M, a | — | protein | 213 | — | A0A5K1K7U1 |
| N, b | — | protein | 227 | — | Q7K6A9 |
Ligands and binding sites
- BO2 · N-[(1R)-1-(dihydroxyboryl)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide · ligand · 6 copies · chains H, I, J, L, M, V, W, X, Z, a
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7LXT · Structure of Plasmodium falciparum 20S proteasome with bound bortezomib · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IAR3
- Every structure of UniProt C6KST3
- Every structure of UniProt Q8IDG3
- Every structure of UniProt Q8IDG2
- Every structure of UniProt Q8IBI3
- Every structure of UniProt Q8IK90
- Every structure of UniProt O77396
- Every structure of UniProt Q8I0U7
- Every structure of UniProt Q8I6T3
- Every structure of UniProt Q8I261
- Every structure of UniProt Q8IKC9
- Every structure of UniProt Q8IJT1
- Every structure of UniProt A0A5K1K7U1
- Every structure of UniProt Q7K6A9
- Elsewhere: RCSB PDB 7LXT · PDBe 7LXT · UniProt Q8IAR3 · UniProt C6KST3 · UniProt Q8IDG3 · UniProt Q8IDG2 · UniProt Q8IBI3 · UniProt Q8IK90 · UniProt O77396 · UniProt Q8I0U7 · UniProt Q8I6T3 · UniProt Q8I261 · UniProt Q8IKC9 · UniProt Q8IJT1 · UniProt A0A5K1K7U1 · UniProt Q7K6A9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.