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UniProt Q8I6T3

20S proteasome beta-2 subunit (Q8I6T3)

20S proteasome beta-2 subunit (UniProt Q8I6T3), EC 3.4.25.1: 14 experimental structures on GenesisL1, 2 ligands bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8I6T3
Protein
20S proteasome beta-2 subunit
EC
3.4.25.1
Experimental structures
14
Predicted models
0
Ligands
2
Pockets
34 · 6 records with a druggable one

Structures

14 records of Q8I6T3 in the MolNFT archive: 14 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5FMGStructure and function based design of Plasmodium-selective proteasome inhibitorselectron microscopyI, W7F16 (best 0.75)
5FMGStructure and function based design of plasmodium-selective proteasome inhibitorselectron microscopyI, W——
6MUVThe structure of the Plasmodium falciparum 20S proteasome in complex with two PA28 activatorselectron microscopyI, W——
6MUVThe structure of the plasmodium falciparum 20S proteasome in complex with two PA28 activatorselectron microscopyI, W——
6MUWThe structure of the Plasmodium falciparum 20S proteasome.electron microscopyI, W—6 (best 0.77)
6MUWThe structure of the plasmodium falciparum 20S proteasome.electron microscopyI, W——
6MUXThe structure of the Plasmodium falciparum 20S proteasome in complex with one PA28 activatorelectron microscopyI, W—3 (best 0.78)
6MUXThe structure of the plasmodium falciparum 20S proteasome in complex with one PA28 activatorelectron microscopyI, W——
7LXTStructure of Plasmodium falciparum 20S proteasome with bound bortezomibelectron microscopyI, WBO27 (best 0.79)
7LXTStructure of plasmodium falciparum 20S proteasome with bound bortezomibelectron microscopyI, WBO2—
7LXUStructure of Plasmodium falciparum 20S proteasome with bound MPI-5electron microscopyI, W——
7LXUStructure of plasmodium falciparum 20S proteasome with bound mpi-5electron microscopyI, W——
8G6FStructure of the Plasmodium falciparum 20S proteasome beta-6 A117D mutant complexed with inhibitor…electron microscopyI, W7F16 (best 0.80)
8W2FPlasmodium falciparum 20S proteasome bound to an inhibitorelectron microscopyI, W—6 (best 0.77)

Ligands

  • 7F1 · (2S)-N-[(E,2S)-1-(1H-indol-3-yl)-4-methylsulfonyl-but-3-en-2-yl]-2-[[(2S)-3-(1H-indol-3-yl)-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]-4-methyl-pentanamide · in 2 records
  • BO2 · N-[(1R)-1-(dihydroxyboryl)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide · in 2 records

Elsewhere

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