Structure of NEDD4L WW3 domain

Structure

x-ray diffraction · 2 distinct chains · 6% helix, 25% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

5 interfaces between chains.

• A–B · 535 Ų buried · 6 hydrogen bonds · protein-protein
• C–D · 529 Ų buried · 6 hydrogen bonds · protein-protein
• A–C · 349 Ų buried · 13 hydrogen bonds · protein-protein
• B–C · 168 Ų buried · 2 hydrogen bonds · protein-protein
• A–D · 156 Ų buried · 2 hydrogen bonds · protein-protein

Compared structures

• 7LP3 · Structure of Nedd4L WW3 domain · the same entry in another collection · chain A against A, TM-score 1.00
• Q96PU5 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase NEDD4-like (Q96PU5) · a predicted model of the same protein · chain A against A, TM-score 0.85
• Q4VCS5 · AlphaFold monomer V2.0 prediction for angiomotin (Q4VCS5) · a predicted model of the same protein · chain B against A, TM-score 0.23

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q96PU5
• Every structure of UniProt Q4VCS5
• Elsewhere: RCSB PDB 7LP3 · PDBe 7LP3 · UniProt Q96PU5 · UniProt Q4VCS5