MolNFT v1 · #181017 · protein
Human U1A protein with F37M and F77M mutations for improved phasing
7LHX · U1 small nuclear ribonucleoprotein a: “Human U1A protein with F37M and F77M mutations for improved phasing”. X-ray diffraction, 1 ligand (NA), 1 pocket (best druggability 0.33). MolNFT v1 #181017 on GenesisL1: 3D structure, binding…
- PDB
- 7LHX
- Type
- protein
- Length
- 96 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- U1 small nuclear ribonucleoprotein a
- UniProt
- P09012
- Ligands
- NA
- Pockets
- 1 · best druggability 0.33
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | U1 small nuclear ribonucleoprotein a | protein | 96 | 32% helix, 25% strand | P09012 |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
- ACT · Acetate ion · additive · 2 copies · chains A
- BME · Beta-mercaptoethanol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.33 | 0.78 | 15 | ACT |
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 7LHX · Human U1A protein with F37M and F77M mutations for improved phasing · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09012
- Elsewhere: RCSB PDB 7LHX · PDBe 7LHX · UniProt P09012
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