MolNFT v1 · #180931 · protein
Structure of importin A3 bound to P50 nls
7LFC · Importin subunit alpha-3: “Structure of importin A3 bound to P50 nls”. X-ray diffraction. MolNFT v1 #180931 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LFC
- Type
- protein
- Length
- 426 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Importin subunit alpha-3; Nuclear factor nf-kappa-B P105 subunit
- UniProt
- O00629, P19838
Structure
x-ray diffraction · 2 distinct chains · 73% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Importin subunit alpha-3 | protein | 414 | 75% helix, 0% strand | O00629 |
| B | Nuclear factor nf-kappa-B P105 subunit | protein | 12 | 0% helix, 0% strand | P19838 |
Interfaces
1 interface between chains.
- A–B · 964 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 7LFC · Structure of importin a3 bound to p50 NLS · the same entry in another collection · chain A against A, TM-score 1.00
- O00629 · AlphaFold monomer V2.0 prediction for importin subunit alpha-3 (O00629) · a predicted model of the same protein · chain A against A, TM-score 0.99
- P19838 · AlphaFold monomer V2.0 prediction for nuclear factor nf-kappa-B P105 subunit (P19838) · a predicted model of the same protein · chain B against A, TM-score 0.37
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00629
- Every structure of UniProt P19838
- Elsewhere: RCSB PDB 7LFC · PDBe 7LFC · UniProt O00629 · UniProt P19838
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