UniProt P19838
Nuclear factor NF-kappa-B p105 subunit (P19838)
Nuclear factor NF-kappa-B p105 subunit (UniProt P19838): 25 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P19838
- Protein
- Nuclear factor NF-kappa-B p105 subunit
- Experimental structures
- 25
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
26 records of P19838 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1MDI | High resolution solution NMR structure of mixed disulfide intermediate between mutant human… | solution nmr | B | — | — |
| 1MDI | High resolution solution NMR structure of mixed disulfide intermediate between mutant human… | solution nmr | B | — | — |
| 1MDJ | High resolution solution NMR structure of mixed disulfide intermediate between human thioredoxin… | solution nmr | B | — | — |
| 1MDJ | High resolution solution NMR structure of mixed disulfide intermediate between human thioredoxin… | solution nmr | B | — | — |
| 1MDK | High resolution solution NMR structure of mixed disulfide intermediate between human thioredoxin… | solution nmr | B | — | — |
| 1MDK | High resolution solution NMR structure of mixed disulfide intermediate between human thioredoxin… | solution nmr | B | — | — |
| 1NFI | I-kappa-B-ALPHA/NF-kappa-B complex | x-ray diffraction | B, D | — | — |
| 1NFI | I-kappa-B-ALPHA/NF-kappa-B complex | x-ray diffraction | B, D | — | — |
| 1SVC | Nfkb P50 homodimer bound to DNA | x-ray diffraction | P | — | — |
| 1SVC | Nfkb P50 homodimer bound to DNA | x-ray diffraction | P | — | — |
| 2DBF | Solution structure of the Death domain in human Nuclear factor NF-kappa-B p105 subunit | solution nmr | A | — | — |
| 2DBF | Solution structure of the death domain in human nuclear factor nf- kappa-B P105 subunit | solution nmr | A | — | — |
| 2O61 | Crystal Structure of NFkB, IRF7, IRF3 bound to the interferon-b enhancer | x-ray diffraction | B | — | — |
| 2O61 | Crystal structure of nfkb, IRF7, IRF3 bound to the interferon-B enhancer | x-ray diffraction | B | — | — |
| 3GUT | Crystal structure of a higher-order complex of p50:RelA bound to the HIV-1 LTR | x-ray diffraction | B, D, F, H | — | — |
| 3GUT | Crystal structure of a higher-order complex of P50:RELA bound to the HIV-1 ltr | x-ray diffraction | B, D, F, H | — | — |
| 7LEQ | Structure of importin a2 bound to p50 NLS | x-ray diffraction | B | — | — |
| 7LEQ | Structure of importin A2 bound to P50 nls | x-ray diffraction | B | — | — |
| 7LET | Structure of importin a2 bound to the p50- and p65-NLSs | x-ray diffraction | B | — | 1 (best 0.32) |
| 7LET | Structure of importin A2 bound to the P50- and P65-nlss | x-ray diffraction | B | — | — |
| 7LF4 | Structure of importin a3 bound to the p50- and p65-NLSs | x-ray diffraction | B, F | — | 2 (best 0.43) |
| 7LF4 | Structure of importin A3 bound to the P50- and P65-nlss | x-ray diffraction | B, F | — | — |
| 7LFC | Structure of importin A3 bound to P50 nls | x-ray diffraction | B | — | — |
| 7RG4 | Importin alpha2 in complex with p50 NLS | x-ray diffraction | B | — | — |
| 7RG4 | Importin ALPHA2 in complex with P50 nls | x-ray diffraction | B | — | — |
| P19838 | AlphaFold monomer V2.0 prediction for nuclear factor nf-kappa-B P105 subunit (P19838) | predicted | A | — | 3 (best 0.53) |
Experiment against prediction
- 1NFI chain B against the predicted model P19838: TM-score 0.99, RMSD 0.46 Å
- 1NFI chain B against the predicted model P19838: TM-score 0.99, RMSD 0.46 Å
- 1SVC chain P against the predicted model P19838: TM-score 0.97, RMSD 1.37 Å
- 1SVC chain P against the predicted model P19838: TM-score 0.97, RMSD 1.37 Å
- 3GUT chain B against the predicted model P19838: TM-score 0.97, RMSD 1.34 Å
- 3GUT chain B against the predicted model P19838: TM-score 0.97, RMSD 1.34 Å
- 2O61 chain B against the predicted model P19838: TM-score 0.96, RMSD 1.43 Å
- 2O61 chain B against the predicted model P19838: TM-score 0.96, RMSD 1.43 Å
- 2DBF chain A against the predicted model P19838: TM-score 0.87, RMSD 1.53 Å
- 2DBF chain A against the predicted model P19838: TM-score 0.87, RMSD 1.53 Å
Elsewhere
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