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MolNFT v1 · #180837 · protein

Pf 06882961 bound to the glucagon-like peptide-1 receptor (glp-1R)

7LCK: “Pf 06882961 bound to the glucagon-like peptide-1 receptor (glp-1R)”. Electron microscopy, 1 ligand (UK4). MolNFT v1 #180837 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7LCK
Type
protein
Length
390 residues
Chains
1
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P43220
Ligands
UK4

Structure

electron microscopy · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
R—protein390—P43220

Ligands and binding sites

  • UK4 · 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid · ligand · chains R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7LCK · PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R) · the same entry in another collection · chain R against R, TM-score 1.00
  • P43220 · AlphaFold monomer V2.0 prediction for glucagon-like peptide 1 receptor (P43220) · a predicted model of the same protein · chain R against A, TM-score 0.81

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