UK4 · 2-[(4-{6-[(4-cyano-2-fluorophenyl)methoxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-{[(2S)-oxetan-2-yl]methyl}-1H-benzimidazole-6-carboxylic acid

Binding sites

UK4 in 7 structures; the first of them:

• 6X1A · Non peptide agonist PF-06882961, bound to Glucagon-Like peptide-1 (GLP-1) Receptor · UK4 R501 · binds SER31, LEU32, TRP33, VAL36, GLN37, LEU141, LYS197, LEU201 and 16 more
• 7LCI · PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex · UK4 R501 · binds SER31, LEU32, TRP33, VAL36, GLN37, GLU138, LEU141, LYS197 and 13 more
• 7LCJ · PF 06882961 bound to the glucagon-like peptide-1 receptor (GLP-1R):Gs complex · UK4 R501 · binds SER31, LEU32, TRP33, VAL36, GLN37, LEU141, LYS197, LEU201 and 15 more
• 6X1A · Non peptide agonist pf-06882961, bound to glucagon-like peptide-1 (glp-1) receptor · UK4 R501 · binds SER31, LEU32, TRP33, VAL36, GLN37, LEU141, LYS197, LEU201 and 13 more
• 7LCI · Pf 06882961 bound to the glucagon-like peptide-1 receptor (glp-1R):GS complex · UK4 R501 · binds SER31, LEU32, TRP33, VAL36, GLN37, GLU138, LEU141, LYS197 and 13 more
• 7LCJ · Pf 06882961 bound to the glucagon-like peptide-1 receptor (glp-1R):GS complex · UK4 R501 · binds SER31, LEU32, TRP33, VAL36, GLN37, LEU141, LYS197, LEU201 and 11 more
• 7LCK · Pf 06882961 bound to the glucagon-like peptide-1 receptor (glp-1R) · UK4 R501 · binds SER31, LEU32, TRP33, VAL36, GLN37, LEU141, LYS197, LEU201 and 10 more

Residues it binds most

LEU 7, PHE 7, GLN 7, THR 7, TRP 7, SER 7, CYS 6, ARG 7, LYS 7, VAL 7 (residue and the binding sites it lines).