MolNFT v1 · #180824 · protein
Crystal structure of epoxyqueuosine reductase queh in complex with gmp from thermotoga maritima
7LC7: “Crystal structure of epoxyqueuosine reductase queh in complex with gmp from thermotoga maritima”. X-ray diffraction, 4 ligands (SF4, 5GP, FE), 1 pocket (best druggability 0.67). MolNFT v1 #180824 on GenesisL1: 3D structure, binding…
- PDB
- 7LC7
- Type
- protein
- Length
- 178 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Epoxyqueuosine reductase queh
- EC
- 1.17.99.6
- UniProt
- Q9WZJ0
- Ligands
- SF4, 5GP, FE, CL
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 56% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Epoxyqueuosine reductase queh (EC 1.17.99.6) | protein | 178 | 56% helix, 11% strand | Q9WZJ0 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · chains A
- 5GP · Guanosine-5'-monophosphate · ligand · chains A
- FE · Fe (III) ion · metal · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 197 | 0.67 | 0.86 | 35 | SF4, 5GP, CL |
Compared structures
- 7LC7 · Crystal structure of epoxyqueuosine reductase QueH in complex with GMP from Thermotoga… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9WZJ0 · AlphaFold monomer V2.0 prediction for epoxyqueuosine reductase queh (Q9WZJ0) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9WZJ0
- Elsewhere: RCSB PDB 7LC7 · PDBe 7LC7 · UniProt Q9WZJ0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.