MolNFT v1 · #180760 · protein

Clobetasol propionate bound to CYP3A5

7LAD: “Clobetasol propionate bound to CYP3A5”. X-ray diffraction, 2 ligands (HEM, XRD). MolNFT v1 #180760 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7LAD
Type: protein
Length: 447 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P20815
Ligands: HEM, XRD

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	447	—	P20815

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A
XRD · Clobetasol propionate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7LAD · Clobetasol propionate bound to CYP3A5 · the same entry in another collection · chain A against A, TM-score 1.00
P20815 · AlphaFold monomer V2.0 prediction for cytochrome P450 3A5 (P20815) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P20815
Elsewhere: RCSB PDB 7LAD · PDBe 7LAD · UniProt P20815

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