DNA polymerase mu, DGTP:AT product state ternary complex, 50 mm MN2+ (225MIN)

Structure

x-ray diffraction · 4 distinct chains.

Ligands and binding sites

• DGT · 2'-deoxyguanosine-5'-triphosphate · ligand · chains A, P
• MN · Manganese (II) ion · metal · 7 copies · chains A, P, D
• NA · Sodium ion · metal · chains A, P
• EDO · 1,2-ethanediol · additive · 4 copies · chains A, T, P
• EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
• DTT · 2,3-dihydroxy-1,4-dithiobutane · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7KT2 · DNA Polymerase Mu, dGTP:At Product State Ternary Complex, 50 mM Mn2+ (225min) · the same entry in another collection · chain A against A, TM-score 1.00
• Q9NP87 · AlphaFold monomer V2.0 prediction for DNA-directed DNA/RNA polymerase mu (Q9NP87) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9NP87
• Elsewhere: RCSB PDB 7KT2 · PDBe 7KT2 · UniProt Q9NP87