MolNFT v1 · #180168 · protein
Cryo-EM structure of the crac channel orai in an open conformation; H206A gain-of-function mutation in complex with an antibody
7KR5: “Cryo-EM structure of the crac channel orai in an open conformation; H206A gain-of-function mutation in…”. Electron microscopy, 1 ligand (CA). MolNFT v1 #180168 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KR5
- Type
- protein
- Length
- 1,438 residues
- Chains
- 12
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9U6B8
- Ligands
- CA
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | — | protein | 127 | — | Q9U6B8 |
| H | — | protein | 116 | — | — |
| L, N, P | — | protein | 109 | — | — |
| M | — | protein | 116 | — | — |
| O | — | protein | 117 | — | — |
Ligands and binding sites
- CA · Calcium ion · metal · chains C, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KR5 · Cryo-EM structure of the CRAC channel Orai in an open conformation; H206A… · the same entry in another collection · chain P against P, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9U6B8
- Elsewhere: RCSB PDB 7KR5 · PDBe 7KR5 · UniProt Q9U6B8
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