MolNFT v1 · #180100 · protein
Asymmetric mtnf-alpha HTNFR1 complex
7KP8: “Asymmetric mtnf-alpha HTNFR1 complex”. X-ray diffraction, 1 ligand (A7G). MolNFT v1 #180100 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KP8
- Type
- protein
- Length
- 673 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P06804, P19438
- Ligands
- A7G
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 140 | — | P06804 |
| B | — | protein | 140 | — | P06804 |
| C | — | protein | 137 | — | P06804 |
| E | — | protein | 130 | — | P19438 |
| F | — | protein | 126 | — | P19438 |
Ligands and binding sites
- A7G · 1-{[2-(difluoromethoxy)phenyl]methyl}-2-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-benzimidazole · ligand · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KP8 · asymmetric mTNF-alpha hTNFR1 complex · the same entry in another collection · chain F against F, TM-score 1.00
- P06804 · AlphaFold monomer V2.0 prediction for tumor necrosis factor (P06804) · a predicted model of the same protein · chain B against A, TM-score 0.98
- P19438 · AlphaFold monomer V2.0 prediction for tumor necrosis factor receptor superfamily member… · a predicted model of the same protein · chain F against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06804
- Every structure of UniProt P19438
- Elsewhere: RCSB PDB 7KP8 · PDBe 7KP8 · UniProt P06804 · UniProt P19438
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