Ligand · A7G
A7G · 1-{[2-(difluoromethoxy)phenyl]methyl}-2-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-benzimidazole
A7G, 1-{[2-(difluoromethoxy)phenyl]methyl}-2-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-benzimidazole (C25 H25 F2 N5 O, 449.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…
- Component
- A7G
- Formula
- C25 H25 F2 N5 O
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
A7G in 4 structures; the first of them:
- 7KP8 · asymmetric mTNF-alpha hTNFR1 complex · A7G C201 · binds LEU57, VAL122, ALA155, LEU156, LEU57, TYR59, TYR118, GLY120 and 10 more
- 7KP9 · asymmetric hTNF-alpha · A7G C201 · binds LYS11, LEU57, VAL123, ILE155, ALA156, LEU157, LEU57, TYR59 and 14 more
- 7KP8 · Asymmetric mtnf-alpha HTNFR1 complex · A7G C201 · binds LEU57, VAL122, ALA155, LEU156, LEU57, TYR59, TYR118, GLY120 and 10 more
- 7KP9 · Asymmetric htnf-alpha · A7G C201 · binds LYS11, LEU57, VAL123, ILE155, ALA156, LEU157, LEU57, TYR59 and 12 more
Residues it binds most
LEU 4, TYR 4, GLY 4, ILE 4, ALA 4, VAL 4, LYS 2, SER 2 (residue and the binding sites it lines).
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