MolNFT v1 · #179957 · protein

Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B(S1303D)

7KL0: “Cocrystal structure of human camkii-alpha (CAMK2A)KINASE domain and GLUN2B(S1303D)”. X-ray diffraction, 1 ligand (UZD). MolNFT v1 #179957 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7KL0
Type: protein
Length: 560 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9UQM7, Q13224
Ligands: UZD

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	268	—	Q9UQM7
C, D	—	protein	12	—	Q13224

Ligands and binding sites

UZD · methyl 6-O-(heptylcarbamoyl)-beta-L-altropyranoside · ligand · 2 copies · chains A, B
EDO · 1,2-ethanediol · additive · 2 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7KL0 · Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) · the same entry in another collection · chain A against A, TM-score 1.00
Q9UQM7 · AlphaFold monomer V2.0 prediction for CALCIUM/CALMODULIN-dependent protein kinase type II… · a predicted model of the same protein · chain A against A, TM-score 0.96
Q13224 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2B (Q13224) · a predicted model of the same protein · chain C against A, TM-score 0.37

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UQM7
Every structure of UniProt Q13224
Elsewhere: RCSB PDB 7KL0 · PDBe 7KL0 · UniProt Q9UQM7 · UniProt Q13224

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.