MolNFT v1 · #179772 · protein + RNA
Structure of human adenosine deaminase acting on dsrna (ADAR2) bound to dsrna containing a 2'-deoxy BENNER'S base Z opposite the edited base
7KFN: “Structure of human adenosine deaminase acting on dsrna (ADAR2) bound to dsrna containing a 2'-deoxy BENNER'S…”. X-ray diffraction, 2 ligands (IHP, ZN). MolNFT v1 #179772 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7KFN
- Type
- protein + RNA
- Length
- 785 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P78563
- Ligands
- IHP, ZN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 384 | — | P78563 |
| B | — | rna | 23 | — | — |
| C | — | rna | 23 | — | — |
| D | — | protein | 355 | — | P78563 |
Ligands and binding sites
- IHP · Inositol hexakisphosphate · ligand · 2 copies · chains A, D
- ZN · Zinc ion · metal · 2 copies · chains A, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7KFN · Structure of Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA containing… · the same entry in another collection · chain A against A, TM-score 1.00
- P78563 · AlphaFold monomer V2.0 prediction for double-stranded RNA-specific editase 1 (P78563) · a predicted model of the same protein · chain D against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P78563
- Elsewhere: RCSB PDB 7KFN · PDBe 7KFN · UniProt P78563
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