MolNFT v1 · #338896 · protein
AlphaFold monomer V2.0 prediction for double-stranded RNA-specific editase 1 (P78563)
P78563: “AlphaFold monomer V2.0 prediction for double-stranded RNA-specific editase 1 (P78563)”. 6 pockets (best druggability 0.84). MolNFT v1 #338896 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P78563
- Type
- protein
- Length
- 741 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
- Molecule
- Double-stranded RNA-specific editase 1
- UniProt
- P78563
- Pockets
- 6 · best druggability 0.84
Structure
1 distinct chain · 26% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Double-stranded RNA-specific editase 1 | protein | 741 | 26% helix, 15% strand | P78563 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 486 | 0.84 | 0.91 | 39 | empty |
| 2 | 1037 | 0.77 | 0.79 | 93 | empty |
| 3 | 297 | 0.57 | 0.77 | 25 | empty |
| 4 | 247 | 0.51 | 0.75 | 26 | empty |
| 5 | 66 | 0.32 | 0.76 | 15 | empty |
Compared structures
- 8E0F · Human Adenosine Deaminase Acting on dsRNA (ADAR2-RD) bound to dsRNA containing a G-G pair… · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 8E4X · Human Adenosine Deaminase Acting on dsRNA (ADAR2-R2D) bound to dsRNA containing a… · an experimental structure of the same protein · chain A against B, TM-score 0.61
- 9D5J · Human Adenosine Deaminase Acting on dsRNA (ADAR2-RD) bound to dsRNA containing… · an experimental structure of the same protein · chain A against B, TM-score 0.60
- 9D5K · Human Adenosine Deaminase Acting on dsRNA (ADAR2-RD) bound to dsRNA containing an… · an experimental structure of the same protein · chain A against B, TM-score 0.59
- 6VFF · Dimer of human adenosine deaminase acting on dsrna (ADAR2) mutant E488Q bound to dsrna… · an experimental structure of the same protein · chain A against B, TM-score 0.58
- 6VFF · Dimer of Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA… · an experimental structure of the same protein · chain A against B, TM-score 0.58
- 5ED1 · Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA sequence… · an experimental structure of the same protein · chain A against D, TM-score 0.53
- 5ED1 · Human adenosine deaminase acting on dsrna (ADAR2) mutant E488Q bound to dsrna sequence… · an experimental structure of the same protein · chain A against D, TM-score 0.53
- 5HP2 · Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA sequence derived from S.… · an experimental structure of the same protein · chain A against D, TM-score 0.53
- 5HP2 · Human adenosine deaminase acting on dsrna (ADAR2) bound to dsrna sequence derived from S.… · an experimental structure of the same protein · chain A against D, TM-score 0.53
- 5HP3 · Human adenosine deaminase acting on dsrna (ADAR2) bound to dsrna sequence derived from S.… · an experimental structure of the same protein · chain A against D, TM-score 0.53
- 5HP3 · Human Adenosine Deaminase Acting on dsRNA (ADAR2) bound to dsRNA sequence derived from S.… · an experimental structure of the same protein · chain A against D, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P78563
- Elsewhere: UniProt P78563 · AlphaFold DB P78563
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.