MolNFT v1 · #167261 · protein + RNA
Dimer of human adenosine deaminase acting on dsrna (ADAR2) mutant E488Q bound to dsrna sequence derived from human GLI1 gene
6VFF: “Dimer of human adenosine deaminase acting on dsrna (ADAR2) mutant E488Q bound to dsrna sequence derived from…”. X-ray diffraction, 2 ligands (IHP, ZN). MolNFT v1 #167261 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6VFF
- Type
- protein + RNA
- Length
- 882 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P78563
- Ligands
- IHP, ZN
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 382 | — | P78563 |
| B | — | protein | 436 | — | P78563 |
| C | — | rna | 32 | — | — |
| D | — | rna | 32 | — | — |
Ligands and binding sites
- IHP · Inositol hexakisphosphate · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, C, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6VFF · Dimer of Human Adenosine Deaminase Acting on dsRNA (ADAR2) mutant E488Q bound to dsRNA… · the same entry in another collection · chain A against A, TM-score 1.00
- P78563 · AlphaFold monomer V2.0 prediction for double-stranded RNA-specific editase 1 (P78563) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P78563
- Elsewhere: RCSB PDB 6VFF · PDBe 6VFF · UniProt P78563
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.