MolNFT v1 · #178617 · protein
Crystal structure of the ni-bound human heavy-chain variant 122H-delta C-star with 2,5-furandihyrdoxamate collected at 100K
7JGK · Ferritin heavy chain: “Crystal structure of the ni-bound human heavy-chain variant 122H-delta C-star with 2,5-furandihyrdoxamate…”. X-ray diffraction, 3 ligands (V9Y, NI, NA), 1 pocket (best druggability 0.35). MolNFT v1 #178617 on…
- PDB
- 7JGK
- Type
- protein
- Length
- 174 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferritin heavy chain
- EC
- 1.16.3.1
- UniProt
- P02794
- Ligands
- V9Y, NI, NA
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferritin heavy chain (EC 1.16.3.1) | protein | 174 | 72% helix, 0% strand | P02794 |
Ligands and binding sites
- V9Y · N~2~,N~5~-dihydroxyfuran-2,5-dicarboxamide · ligand · chains A
- NI · Nickel (II) ion · metal · 3 copies · chains A
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.35 | 0.78 | 16 | empty |
Compared structures
- 7JGK · Crystal Structure of the Ni-bound Human Heavy-chain variant 122H-delta C-star with… · the same entry in another collection · chain A against A, TM-score 1.00
- P02794 · AlphaFold monomer V2.0 prediction for ferritin heavy chain (P02794) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02794
- Elsewhere: RCSB PDB 7JGK · PDBe 7JGK · UniProt P02794
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.