MolNFT v1 · #178595 · protein

GAS41 yeats domain in complex with 5

7JFY: “GAS41 yeats domain in complex with 5”. X-ray diffraction, 1 ligand (V91). MolNFT v1 #178595 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7JFY
Type: protein
Length: 508 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O95619
Ligands: V91

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	—	protein	125	—	O95619
A	—	protein	131	—	O95619
C, D	—	protein	126	—	O95619

Ligands and binding sites

V91 · N-(5-{3-[(2S)-1,3-thiazolidin-2-yl]azetidine-1-carbonyl}thiophen-2-yl)-L-prolinamide · ligand · 4 copies · chains B, A, C, D
EDO · 1,2-ethanediol · additive · 6 copies · chains B, A, C, D
DMS · Dimethyl sulfoxide · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7JFY · GAS41 YEATS domain in complex with 5 · the same entry in another collection · chain B against B, TM-score 1.00
O95619 · AlphaFold monomer V2.0 prediction for yeats domain-containing protein 4 (O95619) · a predicted model of the same protein · chain C against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95619
Elsewhere: RCSB PDB 7JFY · PDBe 7JFY · UniProt O95619

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