MolNFT v1 · #529531 · protein
AlphaFold monomer V2.0 prediction for yeats domain-containing protein 4 (O95619)
O95619: “AlphaFold monomer V2.0 prediction for yeats domain-containing protein 4 (O95619)”. 2 pockets (best druggability 0.35). MolNFT v1 #529531 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O95619
- Type
- protein
- Length
- 227 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x05Dc5F64ec3DDC2CEdF9ba8CD7b6b5056bB42D27
- Molecule
- Yeats domain-containing protein 4
- UniProt
- O95619
- Pockets
- 2 · best druggability 0.35
Structure
1 distinct chain · 33% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Yeats domain-containing protein 4 | protein | 227 | 33% helix, 31% strand | O95619 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.35 | 0.77 | 16 | empty |
| 2 | 54 | 0.32 | 0.77 | 14 | empty |
Compared structures
- 8X15 · Structure of nucleosome-bound SRCAP-C in the apo state · an experimental structure of the same protein · chain A against W, TM-score 0.67
- 5XTZ · Crystal structure of GAS41 yeats bound to H3K27AC peptide · an experimental structure of the same protein · chain A against A, TM-score 0.60
- 8IIY · Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide · an experimental structure of the same protein · chain A against A, TM-score 0.60
- 5Y8V · Crystal structure of GAS41 · an experimental structure of the same protein · chain A against B, TM-score 0.58
- 5R69 · Xchem group deposition -- crystal structure of human YEATS4 in complex with XS038644E · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 7EIF · Crystal structure of GAS41 yeats domain · an experimental structure of the same protein · chain A against A, TM-score 0.57
- 5R68 · Xchem group deposition -- crystal structure of human YEATS4 in complex with FM000199E · an experimental structure of the same protein · chain A against B, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O95619
- Elsewhere: UniProt O95619 · AlphaFold DB O95619
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