GL1X · GenesisL1 explorer

MolNFT v1 · #529531 · protein

AlphaFold monomer V2.0 prediction for yeats domain-containing protein 4 (O95619)

O95619: “AlphaFold monomer V2.0 prediction for yeats domain-containing protein 4 (O95619)”. 2 pockets (best druggability 0.35). MolNFT v1 #529531 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
O95619
Type
protein
Length
227 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x05Dc5F64ec3DDC2CEdF9ba8CD7b6b5056bB42D27
Molecule
Yeats domain-containing protein 4
UniProt
O95619
Pockets
2 · best druggability 0.35

Structure

1 distinct chain · 33% helix, 31% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AYeats domain-containing protein 4protein22733% helix, 31% strandO95619

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1590.350.7716empty
2540.320.7714empty

Compared structures

  • 8X15 · Structure of nucleosome-bound SRCAP-C in the apo state · an experimental structure of the same protein · chain A against W, TM-score 0.67
  • 5XTZ · Crystal structure of GAS41 yeats bound to H3K27AC peptide · an experimental structure of the same protein · chain A against A, TM-score 0.60
  • 8IIY · Crystal structure of MBP fused GAS41 YEATS domain in complex with H3K14ac peptide · an experimental structure of the same protein · chain A against A, TM-score 0.60
  • 5Y8V · Crystal structure of GAS41 · an experimental structure of the same protein · chain A against B, TM-score 0.58
  • 5R69 · Xchem group deposition -- crystal structure of human YEATS4 in complex with XS038644E · an experimental structure of the same protein · chain A against A, TM-score 0.57
  • 7EIF · Crystal structure of GAS41 yeats domain · an experimental structure of the same protein · chain A against A, TM-score 0.57
  • 5R68 · Xchem group deposition -- crystal structure of human YEATS4 in complex with FM000199E · an experimental structure of the same protein · chain A against B, TM-score 0.57

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