MolNFT v1 · #177997 · protein
Odinarchaeota tubulin (odintubulin) H393D mutant, in a protofilament arrangement, bound 78% GTP/22% GDP 1 K+, 1 MG2+
7F1A · Tubulin-like protein: “Odinarchaeota tubulin (odintubulin) H393D mutant, in a protofilament arrangement, bound 78% GTP/22% GDP 1 K+…”. X-ray diffraction, 4 ligands (GTP, GDP, MG), 5 pockets (best druggability 0.56). MolNFT v1…
- PDB
- 7F1A
- Type
- protein
- Length
- 423 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tubulin-like protein
- UniProt
- A0A1Q9N9N5
- Ligands
- GTP, GDP, MG, K
- Pockets
- 5 · best druggability 0.56
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Tubulin-like protein | protein | 423 | 45% helix, 19% strand | A0A1Q9N9N5 |
Ligands and binding sites
- GTP · Guanosine-5'-triphosphate · ligand · chains B
- GDP · Guanosine-5'-diphosphate · ligand · chains B
- MG · Magnesium ion · metal · chains B
- K · Potassium ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 190 | 0.56 | 0.80 | 31 | GTP, GDP, MG |
| 2 | 160 | 0.49 | 0.77 | 22 | empty |
| 3 | 58 | 0.41 | 0.82 | 15 | empty |
| 4 | 53 | 0.32 | 0.77 | 12 | empty |
| 5 | 73 | 0.31 | 0.74 | 14 | empty |
Compared structures
- 7F1A · Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound… · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1Q9N9N5
- Elsewhere: RCSB PDB 7F1A · PDBe 7F1A · UniProt A0A1Q9N9N5
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