MolNFT v1 · #177830 · protein

Odinarchaeota tubulin (odintubulin) H393D mutant, in a protofilament arrangement, bound to 77% GTP/23% and 2 na+

7EVB · Tubulin-like protein: “Odinarchaeota tubulin (odintubulin) H393D mutant, in a protofilament arrangement, bound to 77% GTP/23% and 2…”. X-ray diffraction, 3 ligands (GTP, GDP, NA), 5 pockets (best druggability 0.56). MolNFT v1…

PDB: 7EVB
Type: protein
Length: 422 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tubulin-like protein
UniProt: A0A1Q9N9N5
Ligands: GTP, GDP, NA
Pockets: 5 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	Tubulin-like protein	protein	422	45% helix, 19% strand	A0A1Q9N9N5

Ligands and binding sites

GTP · Guanosine-5'-triphosphate · ligand · chains B
GDP · Guanosine-5'-diphosphate · ligand · chains B
NA · Sodium ion · metal · 2 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	190	0.56	0.80	32	GTP, GDP, NA
2	97	0.44	0.79	19	empty
3	64	0.44	0.82	15	empty
4	61	0.33	0.76	14	empty
5	63	0.30	0.74	15	empty

Compared structures

7EVB · Odinarchaeota tubulin (OdinTubulin) H393D mutant, in a protofilament arrangement, bound… · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1Q9N9N5
Elsewhere: RCSB PDB 7EVB · PDBe 7EVB · UniProt A0A1Q9N9N5

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