MolNFT v1 · #177731 · protein
A mutant of glycosyktransferase in complex with udp and reb D
7ES2 · Glycosyltransferase: “A mutant of glycosyktransferase in complex with udp and reb D”. X-ray diffraction, 2 ligands (UDP, JDO), 3 pockets (best druggability 0.81). MolNFT v1 #177731 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7ES2
- Type
- protein
- Length
- 405 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glycosyltransferase
- EC
- 2.4.1.-
- UniProt
- Q0DPB7
- Ligands
- UDP, JDO
- Pockets
- 3 · best druggability 0.81
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glycosyltransferase (EC 2.4.1.-) | protein | 405 | 44% helix, 15% strand | Q0DPB7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 709 | 0.81 | 0.85 | 69 | UDP, JDO |
| 2 | 75 | 0.56 | 0.87 | 23 | empty |
| 3 | 85 | 0.38 | 0.76 | 14 | empty |
Compared structures
- 7ES2 · a mutant of glycosyktransferase in complex with UDP and Reb D · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0DPB7
- Elsewhere: RCSB PDB 7ES2 · PDBe 7ES2 · UniProt Q0DPB7
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