MolNFT v1 · #177634 · protein

Structure of the human GLUN1/GLUN2A NMDA receptor in the GLYCINE/CPP bound state

7EOQ: “Structure of the human GLUN1/GLUN2A NMDA receptor in the GLYCINE/CPP bound state”. Electron microscopy, 2 ligands (7RC, NAG). MolNFT v1 #177634 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7EOQ
Type: protein
Length: 3,144 residues
Chains: 4
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q12879, Q05586
Ligands: 7RC, NAG

Structure

electron microscopy · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	—	protein	783	—	Q12879
B, D	—	protein	789	—	Q05586

Ligands and binding sites

7RC · (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid · ligand · 2 copies · chains A, C
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7EOQ · Structure of the human GluN1/GluN2A NMDA receptor in the glycine/CPP bound state · the same entry in another collection · chain A against A, TM-score 1.00
Q05586 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 1 (Q05586) · a predicted model of the same protein · chain B against A, TM-score 0.95
Q12879 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2A (Q12879) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q12879
Every structure of UniProt Q05586
Elsewhere: RCSB PDB 7EOQ · PDBe 7EOQ · UniProt Q12879 · UniProt Q05586

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