MolNFT v1 · #177110 · protein
Wt transporter STATE1
7E7S · SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 2: “Wt transporter STATE1”. Electron microscopy, 1 ligand (CA), 15 pockets (best druggability 0.79). MolNFT v1 #177110 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7E7S
- Type
- protein
- Length
- 1,020 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 2
- EC
- 7.2.2.10
- UniProt
- P16615
- Ligands
- CA
- Pockets
- 15 · best druggability 0.79
Structure
electron microscopy · 1 distinct chain · 48% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SARCOPLASMIC/ENDOPLASMIC reticulum calcium ATPase 2 (EC 7.2.2.10) | protein | 1020 | 48% helix, 15% strand | P16615 |
Ligands and binding sites
- CA · Calcium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
15 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1163 | 0.79 | 0.81 | 103 | empty |
| 2 | 523 | 0.71 | 0.81 | 55 | empty |
| 3 | 508 | 0.70 | 0.80 | 59 | empty |
| 4 | 557 | 0.67 | 0.77 | 43 | empty |
| 5 | 290 | 0.62 | 0.80 | 39 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P16615
- Elsewhere: RCSB PDB 7E7S · PDBe 7E7S · UniProt P16615
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