MolNFT v1 · #176781 · protein
Structure of SAR7334-bound TRPC6 at 2.9 ångström
7DXG: “Structure of SAR7334-bound TRPC6 at 2.9 ångström”. Electron microscopy, 6 ligands (Y01, HOR, POV). MolNFT v1 #176781 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7DXG
- Type
- protein
- Length
- 2,792 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y210
- Ligands
- Y01, HOR, POV, 98R, CA, ZN
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 698 | — | Q9Y210 |
Ligands and binding sites
- Y01 · Cholesterol hemisuccinate · ligand · 16 copies · chains A, D, C, B
- HOR · 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile · ligand · 4 copies · chains A, B, C, D
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · ligand · 4 copies · chains A, C, D, B
- 98R · [(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate · ligand · 4 copies · chains A, D, C, B
- CA · Calcium ion · metal · 8 copies · chains A, D, B, C
- ZN · Zinc ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y210
- Elsewhere: RCSB PDB 7DXG · PDBe 7DXG · UniProt Q9Y210
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