MolNFT v1 · #17557 · protein
Crystal structure of yeast cytosine deaminase apo-enzyme: inorganic zinc bound
1OX7: “Crystal structure of yeast cytosine deaminase apo-enzyme: inorganic zinc bound”. X-ray diffraction, 2 ligands (ZN, CA). MolNFT v1 #17557 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1OX7
- Type
- protein
- Length
- 319 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytosine deaminase
- EC
- 3.5.4.1
- UniProt
- Q12178
- Ligands
- ZN, CA
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cytosine deaminase (EC 3.5.4.1) | protein | 158 | 45% helix, 18% strand | Q12178 |
| B | Cytosine deaminase (EC 3.5.4.1) | protein | 161 | 44% helix, 16% strand | Q12178 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 1528 Ų buried · 24 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 14 modified (engineered).
Compared structures
- 1OX7 · Crystal structure of yeast cytosine deaminase apo-enzyme: inorganic zinc bound · the same entry in another collection · chain A against A, TM-score 1.00
- Q12178 · AlphaFold monomer V2.0 prediction for cytosine deaminase (Q12178) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12178
- Elsewhere: RCSB PDB 1OX7 · PDBe 1OX7 · UniProt Q12178
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