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MolNFT v1 · #174974 · protein

The structure of the actin filament uncapping complex mediated by twinfilin

7CCC: “The structure of the actin filament uncapping complex mediated by twinfilin”. X-ray diffraction, 2 ligands (ADP, CA). MolNFT v1 #174974 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7CCC
Type
protein
Length
1,574 residues
Chains
5
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P68135, Q12792, Q5RKN9, Q923G3
Ligands
ADP, CA

Structure

x-ray diffraction · 5 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein357—P68135
B—protein342—Q12792
C—protein269—Q5RKN9
D—protein248—Q923G3
E—protein358—P68135

Ligands and binding sites

  • ADP · Adenosine-5'-diphosphate · ligand · 2 copies · chains A, E
  • CA · Calcium ion · metal · 2 copies · chains A, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7CCC · The structure of the actin filament uncapping complex mediated by twinfilin · the same entry in another collection · chain E against E, TM-score 1.00
  • P68135 · AlphaFold monomer V2.0 prediction for actin, alpha skeletal muscle (P68135) · a predicted model of the same protein · chain A against A, TM-score 0.95
  • Q12792 · AlphaFold monomer V2.0 prediction for twinfilin-1 (Q12792) · a predicted model of the same protein · chain B against A, TM-score 0.60

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