MolNFT v1 · #174397 · protein
Structure of human BETA1 adrenergic receptor bound to norepinephrine and nanobody 6B9
7BU6: “Structure of human BETA1 adrenergic receptor bound to norepinephrine and nanobody 6B9”. X-ray diffraction, 6 ligands (E5E, 480, CLR). MolNFT v1 #174397 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7BU6
- Type
- protein
- Length
- 569 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- D9IEF7
- Ligands
- E5E, 480, CLR, GLC, NA, SO4
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 449 | — | D9IEF7 |
| B | — | protein | 120 | — | — |
Ligands and binding sites
- E5E · Noradrenaline · ligand · chains A
- 480 · (2S)-2,3-dihydroxypropyl octanoate · ligand · chains A
- CLR · Cholesterol · ligand · chains A
- GLC · alpha-D-glucopyranose · sugar · 2 copies · chains A
- NA · Sodium ion · metal · chains A
- SO4 · Sulfate ion · ion · 7 copies · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
- PG4 · Tetraethylene glycol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7BU6 · Structure of human beta1 adrenergic receptor bound to norepinephrine and nanobody 6B9 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D9IEF7
- Elsewhere: RCSB PDB 7BU6 · PDBe 7BU6 · UniProt D9IEF7
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