MolNFT v1 · #174307 · protein
The crystal structure of MLL2 in complex with ASH2L and RBBP5
7BRE: “The crystal structure of MLL2 in complex with ASH2L and RBBP5”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #174307 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7BRE
- Type
- protein
- Length
- 725 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9UBL3, Q9UMN6, Q15291
- Ligands
- ZN
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 179 | — | Q9UBL3 |
| B | — | protein | 164 | — | Q9UMN6 |
| E | — | protein | 164 | — | Q9UMN6 |
| D | — | protein | 179 | — | Q9UBL3 |
| C | — | protein | 20 | — | Q15291 |
| F | — | protein | 19 | — | Q15291 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains B, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7BRE · The crystal structure of MLL2 in complex with ASH2L and RBBP5 · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UBL3 · AlphaFold monomer V2.0 prediction for SET1/ASH2 histone methyltransferase complex subunit… · a predicted model of the same protein · chain A against A, TM-score 0.98
- Q15291 · AlphaFold monomer V2.0 prediction for retinoblastoma-binding protein 5 (Q15291) · a predicted model of the same protein · chain C against A, TM-score 0.43
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UBL3
- Every structure of UniProt Q9UMN6
- Every structure of UniProt Q15291
- Elsewhere: RCSB PDB 7BRE · PDBe 7BRE · UniProt Q9UBL3 · UniProt Q9UMN6 · UniProt Q15291
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.