MolNFT v1 · #172637 · protein
Structure of human mitochondrial RNA polymerase in complex with imt inhibitor.
7A8P: “Structure of human mitochondrial RNA polymerase in complex with imt inhibitor.”. Electron microscopy, 1 ligand (R4Q). MolNFT v1 #172637 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7A8P
- Type
- protein
- Length
- 911 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O00411
- Ligands
- R4Q
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 911 | — | O00411 |
Ligands and binding sites
- R4Q · (3~{R})-1-[(2~{R})-2-[4-(2-chloranyl-4-fluoranyl-phenyl)-2-oxidanylidene-chromen-7-yl]oxypropanoyl]piperidine-3-carboxylic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7A8P · Structure of human mitochondrial RNA polymerase in complex with IMT inhibitor. · the same entry in another collection · chain A against A, TM-score 1.00
- O00411 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase, mitochondrial (O00411) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00411
- Elsewhere: RCSB PDB 7A8P · PDBe 7A8P · UniProt O00411
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