MolNFT v1 · #172565 · protein
Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar
7A6F: “Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar”. Electron microscopy, 2 ligands (CLR, ZQU). MolNFT v1 #172565 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7A6F
- Type
- protein
- Length
- 1,596 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P08183
- Ligands
- CLR, ZQU
Structure
electron microscopy · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1164 | — | P08183 |
| B | — | protein | 214 | — | — |
| C | — | protein | 218 | — | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7A6F · Nanodisc reconstituted human ABCB1 in complex with MRK16 Fab and zosuquidar · the same entry in another collection · chain A against A, TM-score 1.00
- P08183 · AlphaFold monomer V2.0 prediction for ATP-dependent translocase ABCB1 (P08183) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08183
- Elsewhere: RCSB PDB 7A6F · PDBe 7A6F · UniProt P08183
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