Enah EVH1 in complex with ac-[2-cl-F]-[prom-2]-[prom-17]-ome

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 51% strand (DSSP).

Ligands and binding sites

• 2L5 · 2-chloro-L-phenylalanine · ligand · 2 copies · chains A
• 2L6 · (3s,6r,8as)-5-oxo-1,2,3,8A-tetrahydrospiro[indolizine-6,2'-pyrrolidine]-3-carboxylic acid · ligand · 2 copies · chains A
• R0E · Prom-17 · ligand · 2 copies · chains A
• NO3 · Nitrate ion · ion · chains A
• ACY · Acetic acid · additive · 2 copies · chains A
• MOH · Methanol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7A5M · ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-17]-OMe · the same entry in another collection · chain A against A, TM-score 1.00
• Q8N8S7 · AlphaFold monomer V2.0 prediction for protein enabled homolog (Q8N8S7) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q8N8S7
• Elsewhere: RCSB PDB 7A5M · PDBe 7A5M · UniProt Q8N8S7