MolNFT v1 · #171853 · protein

Crystal structure of NRAS (C118S) in complex with GDP and compound 18

6ZIR: “Crystal structure of NRAS (C118S) in complex with GDP and compound 18”. X-ray diffraction, 3 ligands (EZZ, GDP, MG). MolNFT v1 #171853 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ZIR
Type: protein
Length: 163 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P01111
Ligands: EZZ, GDP, MG

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	163	—	P01111

Ligands and binding sites

EZZ · (3~{S})-3-[2-[(dimethylamino)methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one · ligand · 2 copies · chains A
GDP · Guanosine-5'-diphosphate · ligand · chains A
MG · Magnesium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6ZIR · Crystal structure of NRAS (C118S) in complex with GDP and compound 18 · the same entry in another collection · chain A against A, TM-score 1.00
P01111 · AlphaFold monomer V2.0 prediction for GTPase NRAS (P01111) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01111
Elsewhere: RCSB PDB 6ZIR · PDBe 6ZIR · UniProt P01111

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