MolNFT v1 · #171222 · protein

Structure of the TRIM69 ring domain

6YXE · E3 ubiquitin-protein ligase TRIM69: “Structure of the TRIM69 ring domain”. X-ray diffraction, 1 ligand (ZN). MolNFT v1 #171222 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6YXE
Type: protein
Length: 161 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E3 ubiquitin-protein ligase TRIM69
EC: 2.3.2.27
UniProt: Q86WT6
Ligands: ZN

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27)	protein	89	38% helix, 13% strand	Q86WT6
B	E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27)	protein	72	40% helix, 17% strand	Q86WT6

Ligands and binding sites

ZN · Zinc ion · metal · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 295 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

6YXE · Structure of the Trim69 RING domain · the same entry in another collection · chain A against A, TM-score 1.00
Q86WT6 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM69 (Q86WT6) · a predicted model of the same protein · chain B against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86WT6
Elsewhere: RCSB PDB 6YXE · PDBe 6YXE · UniProt Q86WT6

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