MolNFT v1 · #473274 · protein

AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM69 (Q86WT6)

Q86WT6: “AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM69 (Q86WT6)”. 2 pockets (best druggability 0.47). MolNFT v1 #473274 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q86WT6
Type: protein
Length: 500 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x21ec5109EE01C0d4D6bcB2E62cbe36fe671Fafd7
Molecule: E3 ubiquitin-protein ligase TRIM69
UniProt: Q86WT6
Pockets: 2 · best druggability 0.47

Structure

1 distinct chain · 38% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 ubiquitin-protein ligase TRIM69	protein	500	38% helix, 19% strand	Q86WT6

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	201	0.47	0.74	28	empty
2	196	0.45	0.73	26	empty

Compared structures

4NQJ · Structure of coiled-coil domain · an experimental structure of the same protein · chain A against C, TM-score 0.21
4NQJ · Structure of coiled-coil domain · an experimental structure of the same protein · chain A against C, TM-score 0.21
6YXE · Structure of the TRIM69 ring domain · an experimental structure of the same protein · chain A against A, TM-score 0.16
6YXE · Structure of the Trim69 RING domain · an experimental structure of the same protein · chain A against A, TM-score 0.16

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86WT6
Elsewhere: UniProt Q86WT6 · AlphaFold DB Q86WT6

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