UniProt Q86WT6
E3 ubiquitin-protein ligase TRIM69 (Q86WT6)
E3 ubiquitin-protein ligase TRIM69 (UniProt Q86WT6), EC 2.3.2.27: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q86WT6
- Protein
- E3 ubiquitin-protein ligase TRIM69
- EC
- 2.3.2.27
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
5 records of Q86WT6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4NQJ | Structure of coiled-coil domain | x-ray diffraction | A, B, C | — | — |
| 4NQJ | Structure of coiled-coil domain | x-ray diffraction | A, B, C | — | — |
| 6YXE | Structure of the Trim69 RING domain | x-ray diffraction | A, B | ZN | — |
| 6YXE | Structure of the TRIM69 ring domain | x-ray diffraction | A, B | ZN | — |
| Q86WT6 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase TRIM69 (Q86WT6) | predicted | A | — | 2 (best 0.47) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 6YXE chain B against the predicted model Q86WT6: TM-score 0.94, RMSD 0.96 Å
- 6YXE chain B against the predicted model Q86WT6: TM-score 0.94, RMSD 0.96 Å
- 6YXE chain A against the predicted model Q86WT6: TM-score 0.83, RMSD 1.78 Å
- 6YXE chain A against the predicted model Q86WT6: TM-score 0.83, RMSD 1.78 Å
- 4NQJ chain C against the predicted model Q86WT6: TM-score 0.55, RMSD 3.16 Å
- 4NQJ chain C against the predicted model Q86WT6: TM-score 0.55, RMSD 3.16 Å
- 4NQJ chain A against the predicted model Q86WT6: TM-score 0.55, RMSD 2.94 Å
- 4NQJ chain A against the predicted model Q86WT6: TM-score 0.55, RMSD 2.94 Å
- 4NQJ chain B against the predicted model Q86WT6: TM-score 0.53, RMSD 3.99 Å
- 4NQJ chain B against the predicted model Q86WT6: TM-score 0.53, RMSD 3.99 Å
Elsewhere
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