Structure of the AMPA receptor GLUA2O ligand-binding domain (S1S2J) in complex with the compound ( S) - 1- [2'-amino-2'-carboxyethyl]-6- methyl-5 ,7- DIHYDROPYRROLO[3,4-D]PYRIMIDIN-2,4(1H,3H)-dione at resolution 1.00A

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• CG8 · (2~{S})-2-azanyl-3-[6-methyl-2,4-bis(oxidanylidene)-5, 7-dihydropyrrolo[3,4-d]pyrimidin-1-yl]propanoic acid · ligand · chains A
• LI · Lithium ion · metal · chains A
• SO4 · Sulfate ion · ion · 4 copies · chains A
• CL · Chloride ion · ion · 2 copies · chains A
• GOL · Glycerol · additive · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6YK4 · Structure of the AMPA receptor GluA2o ligand-binding domain (S1S2J) in complex with the… · the same entry in another collection · chain A against A, TM-score 1.00
• P19491 · AlphaFold monomer V2.0 prediction for glutamate receptor 2 (P19491) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P19491
• Elsewhere: RCSB PDB 6YK4 · PDBe 6YK4 · UniProt P19491