MolNFT v1 · #170620 · protein
Saftsz-UCM151 (comp. 18)
6YD5 · Cell division protein ftsz: “Saftsz-UCM151 (comp. 18)”. X-ray diffraction, 4 ligands (GDP, MB3, OM8), 3 pockets (best druggability 0.65). MolNFT v1 #170620 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6YD5
- Type
- protein
- Length
- 307 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell division protein ftsz
- UniProt
- P0A031
- Ligands
- GDP, MB3, OM8, K
- Pockets
- 3 · best druggability 0.65
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell division protein ftsz | protein | 307 | 43% helix, 24% strand | P0A031 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains A
- MB3 · 1-methylpyrrolidin-2-one · ligand · chains A
- OM8 · 3-[(3-chlorophenyl)methoxy]-2,6-bis(fluoranyl)benzamide · ligand · chains A
- K · Potassium ion · metal · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 156 | 0.65 | 0.86 | 25 | OM8 |
| 2 | 235 | 0.61 | 0.81 | 40 | GDP, MB3, EDO |
| 3 | 95 | 0.47 | 0.80 | 17 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A031
- Elsewhere: RCSB PDB 6YD5 · PDBe 6YD5 · UniProt P0A031
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