MolNFT v1 · #170482 · protein

Structure of full-length CD20 in complex with rituximab Fab

6Y90: “Structure of full-length CD20 in complex with rituximab Fab”. Electron microscopy, 3 ligands (MYS, Y01, PC1). MolNFT v1 #170482 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6Y90
Type: protein
Length: 1,218 residues
Chains: 6
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P11836
Ligands: MYS, Y01, PC1

Structure

electron microscopy · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	172	—	P11836
C, H	—	protein	224	—	—
D, L	—	protein	213	—	—

Ligands and binding sites

MYS · Pentadecane · ligand · 10 copies · chains A, B
Y01 · Cholesterol hemisuccinate · ligand · 8 copies · chains A, B
PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6Y90 · Structure of full-length CD20 in complex with Rituximab Fab · the same entry in another collection · chain L against L, TM-score 1.00
P11836 · AlphaFold monomer V2.0 prediction for B-lymphocyte antigen CD20 (P11836) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P11836
Elsewhere: RCSB PDB 6Y90 · PDBe 6Y90 · UniProt P11836

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