UniProt P11836
B-lymphocyte antigen CD20 (P11836)
B-lymphocyte antigen CD20 (UniProt P11836): 18 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 43 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P11836
- Protein
- B-lymphocyte antigen CD20
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 43 · 7 records with a druggable one
Structures
19 records of P11836 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OSL | Crystal structure of Rituximab Fab in complex with an epitope peptide | x-ray diffraction | P, Q | — | — |
| 2OSL | Crystal structure of rituximab Fab in complex with an epitope peptide | x-ray diffraction | P, Q | — | — |
| 3BKY | Crystal Structure of Chimeric Antibody C2H7 Fab in complex with a CD20 Peptide | x-ray diffraction | P | — | — |
| 3BKY | Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide | x-ray diffraction | P | — | — |
| 3PP4 | Epitope characterization and crystal structure of GA101 provide insights into the molecular basis… | x-ray diffraction | P | — | — |
| 3PP4 | Epitope characterization and crystal structure of GA101 provide insights into the molecular basis… | x-ray diffraction | P | — | — |
| 6VJA | Structure of CD20 in complex with rituximab Fab | electron microscopy | C, D | Y01 | 5 (best 0.86) |
| 6VJA | Structure of CD20 in complex with rituximab Fab | electron microscopy | C, D | Y01 | — |
| 6Y90 | Structure of full-length CD20 in complex with Rituximab Fab | electron microscopy | A, B | Y01, PC1, MYS | 7 (best 0.87) |
| 6Y90 | Structure of full-length CD20 in complex with rituximab Fab | electron microscopy | A, B | Y01, PC1, MYS | — |
| 6Y92 | Structure of full-length CD20 in complex with Ofatumumab Fab | electron microscopy | A, B | Y01 | 8 (best 0.84) |
| 6Y92 | Structure of full-length CD20 in complex with ofatumumab Fab | electron microscopy | A, B | Y01 | — |
| 6Y97 | Structure of full-length CD20 in complex with Obinutuzumab Fab | electron microscopy | A, B | — | 7 (best 0.78) |
| 6Y97 | Structure of full-length CD20 in complex with obinutuzumab Fab | electron microscopy | A, B | — | — |
| 6Y9A | Structure of full-length CD20 in complex with Obinutuzumab Fab | electron microscopy | A, B | — | 11 (best 0.77) |
| 6Y9A | Structure of full-length CD20 in complex with obinutuzumab Fab | electron microscopy | A, B | — | — |
| 8VGN | CryoEM structure of CD20 in complex with wild type Rituximab Fab | electron microscopy | G, I | — | 1 (best 0.84) |
| 8VGO | CryoEM structure of CD20 in complex with engineered conformationally rigid Rituximab.4DS Fab | electron microscopy | G, I | — | 4 (best 0.85) |
| P11836 | AlphaFold monomer V2.0 prediction for B-lymphocyte antigen CD20 (P11836) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8VGN chain I against the predicted model P11836: TM-score 0.97, RMSD 0.84 Å
- 8VGN chain G against the predicted model P11836: TM-score 0.97, RMSD 0.85 Å
- 8VGO chain I against the predicted model P11836: TM-score 0.96, RMSD 0.99 Å
- 8VGO chain G against the predicted model P11836: TM-score 0.96, RMSD 1.00 Å
- 6Y90 chain B against the predicted model P11836: TM-score 0.96, RMSD 1.10 Å
- 6Y90 chain B against the predicted model P11836: TM-score 0.96, RMSD 1.10 Å
- 6Y90 chain A against the predicted model P11836: TM-score 0.96, RMSD 1.10 Å
- 6Y90 chain A against the predicted model P11836: TM-score 0.96, RMSD 1.10 Å
- 6Y97 chain A against the predicted model P11836: TM-score 0.94, RMSD 1.31 Å
- 6Y97 chain A against the predicted model P11836: TM-score 0.94, RMSD 1.31 Å
Elsewhere
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