MolNFT v1 · #169983 · protein
The external aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-S377A with inhibitor 2-({[4- (TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL dihydrogen phosphate (F9F) at the alpha-site, cesium ion at the metal coordination site, and (E)-N-({3-hydroxy-2-methyl-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4- YL}METHYLIDENE)-L-serine (kou) at the beta-site
6XSY: “The external aldimine crystal structure of salmonella typhimurium tryptophan synthase mutant beta-S377A with…”. X-ray diffraction, 3 ligands (F9F, CS, CL). MolNFT v1 #169983 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6XSY
- Type
- protein
- Length
- 665 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P00929, P0A2K1
- Ligands
- F9F, CS, CL
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 268 | — | P00929 |
| B | — | protein | 397 | — | P0A2K1 |
Ligands and binding sites
- F9F · 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate · ligand · chains A, B
- CS · Cesium ion · metal · 2 copies · chains B
- CL · Chloride ion · ion · 9 copies · chains A, B
- DMS · Dimethyl sulfoxide · additive · 20 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XSY · The external aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00929
- Every structure of UniProt P0A2K1
- Elsewhere: RCSB PDB 6XSY · PDBe 6XSY · UniProt P00929 · UniProt P0A2K1
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