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MolNFT v1 · #169095 · protein + DNA

Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin

6X0M: “Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin”. Electron microscopy. MolNFT v1 #169095 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6X0M
Type
protein + DNA
Length
1,472 residues
Chains
8
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q9NWY4, Q9UGN5

Structure

electron microscopy · 8 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
O—protein246—Q9NWY4
P—protein470—Q9UGN5
o—protein242—Q9NWY4
p—protein468—Q9UGN5
I—dna12——
J—dna12——
i—dna11——
j—dna11——

Compared structures

  • 6X0M · Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin · the same entry in another collection · chain j against j, TM-score 1.00
  • Q9NWY4 · AlphaFold monomer V2.0 prediction for histone parylation factor 1 (Q9NWY4) · a predicted model of the same protein · chain o against A, TM-score 0.98
  • Q9UGN5 · AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase 2 (Q9UGN5) · a predicted model of the same protein · chain p against A, TM-score 0.93

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