MolNFT v1 · #168988 · protein
SOX2 bound to importin-alpha 3
6WX8: “SOX2 bound to importin-alpha 3”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #168988 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WX8
- Type
- protein
- Length
- 999 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O00629, P48431
- Ligands
- SO4
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 419 | — | O00629 |
| B | — | protein | 82 | — | P48431 |
| C | — | protein | 417 | — | O00629 |
| D | — | protein | 81 | — | P48431 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 5 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6WX8 · SOX2 bound to Importin-alpha 3 · the same entry in another collection · chain D against D, TM-score 1.00
- O00629 · AlphaFold monomer V2.0 prediction for importin subunit alpha-3 (O00629) · a predicted model of the same protein · chain C against A, TM-score 0.99
- P48431 · AlphaFold monomer V2.0 prediction for transcription factor sox-2 (P48431) · a predicted model of the same protein · chain D against A, TM-score 0.75
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00629
- Every structure of UniProt P48431
- Elsewhere: RCSB PDB 6WX8 · PDBe 6WX8 · UniProt O00629 · UniProt P48431
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