MolNFT v1 · #168399 · protein
Crystal structure of human NAA50 in complex with an inhibitor (compound 3) identified using DNA encoded library technology
6WFG: “Crystal structure of human NAA50 in complex with an inhibitor (compound 3) identified using DNA encoded…”. X-ray diffraction, 2 ligands (COA, U3V). MolNFT v1 #168399 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WFG
- Type
- protein
- Length
- 453 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9GZZ1
- Ligands
- COA, U3V
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 150 | — | Q9GZZ1 |
| C | — | protein | 152 | — | Q9GZZ1 |
| E | — | protein | 151 | — | Q9GZZ1 |
Ligands and binding sites
- COA · Coenzyme A · ligand · 3 copies · chains A, C, E
- U3V · (2S)-N-[(2S)-3-[1-(3-tert-butyl-1-methyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1-(methylamino)-1-oxopropan-2-yl]-6-oxopiperidine-2-carboxamide · ligand · 3 copies · chains A, C, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6WFG · Crystal structure of human Naa50 in complex with an inhibitor (compound 3) identified… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9GZZ1 · AlphaFold monomer V2.0 prediction for N-alpha-acetyltransferase 50 (Q9GZZ1) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GZZ1
- Elsewhere: RCSB PDB 6WFG · PDBe 6WFG · UniProt Q9GZZ1
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